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| CAS No.: | 110-15-6 |
|---|---|
| Name: | Succinic acid |
| Article Data: | 1276 |
| Cas Database | |
| Molecular Structure: | |
|
|
|
| Formula: | C4H6O4 |
| Molecular Weight: | 118.089 |
| Synonyms: | 1,2-Ethanedicarboxylic acid;1,4-Butanedioic acid;A 12084;Amberacid;Asuccin;Dihydrofumaric acid;Katasuccin;NSC 106449;NSC 25949;Wormwoodacid;Yantar-antitox;Succinic Acid 99.5%;succinic acid(amber acid);Butanedioicacid; |
| EINECS: | 203-740-4 |
| Density: | 1.552 g/cm3 |
| Melting Point: | 185 °C |
| Boiling Point: | 236.1 °C at 760 mmHg |
| Flash Point: | 110.9 °C |
| Solubility: | Water Solubility: 80 g/L (20 °C) |
| Appearance: | White crystalline powder |
| Hazard Symbols: |
 Xi
|
| Risk Codes: | 36/37/38 |
| Safety: | 26-37/39 |
| Transport Information: | UN 3265 8/PG 3 |
| PSA: | 74.60000 |
| LogP: | -0.06420 |
| Conditions | Yield |
|---|---|
| With oxygen; trifluoroacetic acid; sodium nitrite at 0 - 20℃; for 5.25h; Product distribution / selectivity; | 100% |
| With nitric acid |
| Conditions | Yield |
|---|---|
| With palladium/alumina; hydrogen In water at 80℃; for 6.5h; | 100% |
| With samarium diiodide In tetrahydrofuran for 0.0833333h; Ambient temperature; | 99% |
| With hydrogen; NPF-1 (palladium 0.2 wt percent, nickel 0.2 wt percent, iron 0.07 wt percent on carbon) modified with maleic acid In water at 90 - 100℃; under 15201 Torr; Product distribution / selectivity; Autoclave; Inert atmosphere; | 99.5% |
3,9-dioxo-6,12-dihydroxy-1,2,7,8-tetraoxacyclododecane
succinic acid
| Conditions | Yield |
|---|---|
| In octane for 2.5h; Product distribution; Heating; other reagent - H2 + Lindlar's cat.; | 100% |
5-hydroxy-2-(5H)-furanone
succinic acid
| Conditions | Yield |
|---|---|
| With sodium hydroxide at 70 - 80℃; pH=9 - 10; | 100% |
| Conditions | Yield |
|---|---|
| With oxygen; trifluoroacetic acid; sodium nitrite at 0 - 20℃; for 5.25h; Product distribution / selectivity; | 100% |
| Conditions | Yield |
|---|---|
| With hydrogen; POUB-0.8 (0.8 wt percent palladium on carbon) modified with succinic acid In water at 120℃; under 10 - 15 Torr; Product distribution / selectivity; Industry scale; Inert atmosphere; Autoclave; | 99.7% |
| With formic acid In water at 79.84℃; for 3h; Catalytic behavior; Reagent/catalyst; Autoclave; | 99% |
| With palladium on activated charcoal; water; hydrogen at 60 - 100℃; under 3750.38 - 7500.75 Torr; for 3h; Time; Sealed tube; Large scale; | 95% |
| Conditions | Yield |
|---|---|
| With formic acid; paraquat dichloride In water at 40℃; for 7h; Clostridium formicoaceticum; | 99% |
| With hydrogen; 1.0 wt percent palladium, 2.0 wt percent nickel on fibrous asbestos modified with fumaric acid In water at 120℃; under 19001.3 Torr; Autoclave; Inert atmosphere; | 99.1% |
| With hydrogen iodide; hydrogen In propionic acid at 160℃; under 25858.1 Torr; for 2h; Kinetics; Reagent/catalyst; | 99% |
maleic acid
A
tetrahydrofuran
B
4-butanolide
C
Butane-1,4-diol
D
succinic acid
E
acetic acid
| Conditions | Yield |
|---|---|
| With hydrogen; 0.5 percent Pd on Rutile TiO2 at 110℃; Product distribution / selectivity; | A 0.37% B 0.28% C 0.37% D 98.89% E 0.08% |
maleic acid
A
tetrahydrofuran
B
4-butanolide
C
methanol
D
Butane-1,4-diol
E
malic acid
F
succinic acid
G
acetic acid
H
butan-1-ol
| Conditions | Yield |
|---|---|
| With hydrogen; 0.5percent Pd on Rutile TiO2 at 110℃; Product distribution / selectivity; | A 0.45% B 0.06% C 0% D 0.21% E 0.36% F 98.73% G 0.04% H 0.08% |
| Conditions | Yield |
|---|---|
| With sodium chloride In N,N-dimethyl-formamide at 110℃; for 5h; Temperature; | 98.5% |
| With sodium hypobromide; water; potassium carbonate In N,N-dimethyl acetamide at 140℃; pH=7; Temperature; Reagent/catalyst; pH-value; | 90% |
| With hydrogen bromide; oxygen; manganese (II) acetate tetrahydrate; cobalt(II) diacetate tetrahydrate In water; acetic acid at 180℃; under 22502.3 Torr; for 3h; | 12% |
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Molecular formula: C4H6O4
Molar mass: 118.09 g/mol
EINECS: 203-740-4
Index of Refraction: 1.477
Density: 1.408 g/cm3
Flash Point: 110.9 °C
Melting point: 185 °C
storage temp.: Store at RT.
Water Solubility: 80 g/L (20 °C)
Enthalpy of Vaporization: 52.09 kJ/mol
Boiling Point: 236.1 °C at 760 mmHg
Vapour Pressure: 0.0165 mmHg at 25 °C
Appearance: White crystals or shiny white odorless crystalline powder
Structure of Succinic acid (CAS NO.110-15-6):
IUPAC Name: Butanedioic acid
Product Category of Succinic acid (CAS NO.110-15-6): Succinic Series;alpha,omega-Alkanedicarboxylic Acids;Monofunctional & alpha,omega-Bifunctional Alkanes
Succinic acid (CAS NO.110-15-6) was chiefly used externally for rheumatic aches and pains, and internally in inveterate gleets.
| 1. | eye-rbt 1179 µg SEV | AJOPAA American Journal of Ophthalmology. 29 (1946),1363. | ||
| 2. | dni-hmn:fbr 20 mmol/L | MUREAV Mutation Research. 183 (1987),89. | ||
| 3. | orl-rat LD50:2260 mg/kg | KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) #82-0158 . |
Succinic acid (CAS NO.110-15-6) hasn't been listed as a carcinogen by NTP, IARC, ACGIH, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.
SUCCINIC ACID's reported in EPA TSCA Inventory.
Moderately toxic by subcutaneous route. A severe eye irritant. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes: 
Xi
Risk Statements: 37/38-41-36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
R37/38:Irritating to respiratory system and skin.
R41:Risk of serious damage to the eyes.
Safety Statements: 26-36/37/39-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S37/39:Wear suitable gloves and eye/face protection.
Succinic acid , its cas register number is 110-15-6. It also can be called Butanedioic acid ; Amber acid ; and 1,2-Ethanedicarboxylic acid . It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: first, should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly, get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While, it's inhaled: Remove from exposure and move to fresh air immediately. Give artificial respiration while not breathing. When breathing is difficult, give oxygen. And as soon as to get medical aid. Then you have the ingesting of the product: Wash mouth out with water, and get medical aid immediately.
In addition, Succinic acid (CAS NO.110-15-6) could be stable under normal temperatures and pressures. It is not compatible with incompatible materials, reducing agents, bases, and you must not take it with incompatible materials. And also prevent it to broken down into hazardous decomposition products: carbon monoxide, carbon dioxide.
