China (Mainland) 
basic information of tadalafil
product name: tadalafil
chemical name: (6r,12ar)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione;
tadalafil
appearance: white powder
content: 99.5%min
cas #:171596-29-5
test method: hplc
molecular formula:c22h19n3o4
molecular weight: 389.40
specifications of tadalafil
|
tests |
specifications |
result |
|
description |
white crystalline powder |
white crystalline powder |
|
solubility |
diffluent in ach, slightly soluble in methanol,almost insoluble in chloroform |
complies |
|
identification |
|
|
|
hplc |
comply with standard |
complies |
|
a292/a227 |
2.28~2.42 |
2.36 |
|
ir |
ir should comply with the reference standard spectrum. |
complies |
|
citrate |
positive |
complies |
|
acidity |
3.0~5.0 |
3.63 |
|
loss on drying |
≤1.0% |
0.32% |
|
residue on ignition |
≤0.1% |
0.04% |
|
heavy metals |
≤20ppm |
complies |
|
relevant impurity |
≤0.5% |
0.28% |
|
methanol |
≤0.3% |
0.02% |
|
methylene dichloride |
≤0.06% |
0.017% |
|
n,n-dimethyl formamide |
≤0.088% |
not detected |
|
assay |
98.5~101.5% |
99.6% |
function of tadalafil
tadalafil is an oral drug for the treatment of ed, used in the treatment of erectile dysfunction and premature ejaculation, erectile function impairment and premature ejaculation has very significant improvements
packing & storage of tadalafil
|
packaging |
1kg with double plastic container inside/aluminum foil bag outside. 25kg with double plastic container inside/fiber drum outside. |
|
storage |
store in cool & dry place, keep away from strong light and heat. |
|
shelf life |
2 years if sealed and store away from direct sun light. |
company information
founded in 2012 as a professional international pharmaceutical corporation, headquartered in xi'an (china), xi'an kono chemical co., ltd. is a leading producer of standardized herbal extracts, natural active ingredients and apis
for pharmaceutical, health food and cosmetic industries.
annually, more than 3,000 tons of a wide range of herbal extracts and natural active substances are extracted at thexi'an kono chemical co., ltd. manufacturing plant near xi'an, china. these extracts are in compliance with worldwide gmp, haccp norms, international pharmacopoeias, and international regulations.
the botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according
to methods developed by kono. they include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and
development, analyses, processes and machinery, the rapeutic applications on a scientific basis.
with our phytopharmaceutical background and knowledge through experience, kono can also provide a wide
range of analytical services and reference substances to our clients. in addition, we also manufacture pharmaceutical raw materials of nucleotide species, mainly including as below: sam-e tosylate disulfate; sam-e 1,4-butanedisulfonate; polycytidylic acid; polyinosinic acid; adenosine triphosphate disodium; and cytidine triphosphate disodium; these items are our strongest advantage in china. meanwhile, we can do custom made pharmaceutical ingredients depending on our professional experts in the pharmaceutical and chemistry industry.
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