CAS No.4065-45-6,2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid Suppliers,MSDS download

Products Categories

Pharmaceutical (160)
Organic Chemicals (78)
Others (73)
Catalyst and Auxiliary (26)
Materials (8)
Reagent (7)
Food Additives (2)
Basic Inorganic Chemicals (2)
Plant Extract (1)

Basic Information

Molecular Structure:
CAS No.:	4065-45-6
Name:	2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid
Article Data:	14
Cas Database

Formula:	C₁₄H₁₂O₆S
Molecular Weight:	308.312
Synonyms:	1-Phenol-4-sulfonicacid, 2-benzoyl-5-methoxy- (6CI);2-Hydroxy-4-methoxy-5-sulfobenzophenone;2-Methoxy-4-hydroxy-5-benzoylbenzenesulfonic acid;3-Benzoyl-4-hydroxy-6-methoxybenzenesulfonic acid;5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid;Benzophenone 4;Escalol 577;MS 40;NSC 60584;Seesorb 101S;Spectra-Sorb UV 284;Sulisobenzone;
EINECS:	223-772-2
Density:	1.449 g/cm³
Melting Point:	170 °C
Boiling Point:	0°C
Flash Point:	0°C
Solubility:	N/A
Appearance:	white to yellowish powder
Hazard Symbols:	Xi
Risk Codes:	36/37/38
Safety:	26-36-37/39-36/37/39-27
Transport Information:	N/A
PSA:	109.28000
LogP:	2.95930

Synthetic route

: 131-57-7
Benzophenone-3

: 4065-45-6
2-hydroxy-4-methoxybenzophenone-5-sulfonic acid

Conditions

Conditions	Yield
With sulfur trioxide; acetic acid In 1,2-dichloro-ethane at 25℃; for 3h; Inert atmosphere;	98.82%
With chlorosulfonic acid In ethyl acetate at 45℃; Temperature;	96%
With chlorosulfonic acid In phthalic acid dimethyl ester
With chlorosulfonic acid at 25℃; for 20h; Inert atmosphere; Autoclave;

: 4-benzoyloxy-2-methoxybenzenesulfonic acid

: 4065-45-6
2-hydroxy-4-methoxybenzophenone-5-sulfonic acid

Conditions

Conditions	Yield
In methanol at 35℃; for 0.333333h; UVB irradiation;

: 4065-45-6
2-hydroxy-4-methoxybenzophenone-5-sulfonic acid

: 108-90-7
chlorobenzene

: 817203-48-8
C14H11O6S(1-)*C18H12Cl3S(1+)

Conditions

Conditions	Yield
Stage #1: chlorobenzene With thionyl chloride; aluminum (III) chloride at 20 - 150℃; for 5h; Stage #2: With water at 60℃; for 1h; Stage #3: 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid In water for 4h;	79%

: 4065-45-6
2-hydroxy-4-methoxybenzophenone-5-sulfonic acid

: 158547-83-2
3,5-dichloro-2-hydroxy-4-methoxybenzophenone

Conditions

Conditions	Yield
With trichloroisocyanuric acid; sodium hydrogencarbonate In water	33%

: 4065-45-6
2-hydroxy-4-methoxybenzophenone-5-sulfonic acid

: 1631050-95-7
5-benzoyl-3-chloro-4-hydroxy-2-methoxybenzenesulfonic acid

Conditions

Conditions	Yield
With hydrogenchloride; sodium hypochlorite In water for 2h; Cooling with ice;	18%

: 4065-45-6
2-hydroxy-4-methoxybenzophenone-5-sulfonic acid

: 1609-47-8
diethyl dicarbonate

: 19337-04-3
2--4-methoxy-5-sulfo-benzophenon

: 4065-45-6
2-hydroxy-4-methoxybenzophenone-5-sulfonic acid

: 77-78-1
dimethyl sulfate

: sodium 2,4-dimethoxy-5-benzoylbenzenesulfonate

Conditions

Conditions	Yield
With sodium hydroxide Heating;

: 4065-45-6
2-hydroxy-4-methoxybenzophenone-5-sulfonic acid

: 121715-18-2
5-benzoyl-4-hydroxy-2-methoxy-benzenesulfonyl chloride

: 2-[2-[2-chloro-3-[(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-1,3,3-trimethyl-3H-indolium bromide

: 4065-45-6
2-hydroxy-4-methoxybenzophenone-5-sulfonic acid

: 2-[2-[2-chloro-3-[(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-1,3,3-trimethyl-3H-indolium, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid salt

Conditions

Conditions	Yield
Stage #1: 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid With sodium hydrogencarbonate In 1-methoxy-2-propanol; water Stage #2: 2-[2-[2-chloro-3-[(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-1,3,3-trimethyl-3H-indolium bromide In 1-methoxy-2-propanol; water at 20℃; for 2.16667h; In the dark;

: 4065-45-6
2-hydroxy-4-methoxybenzophenone-5-sulfonic acid

: 99-09-2
3-nitro-aniline

: 1243203-31-7
1-[2-hydroxy-4-methoxy-5-(3-nitrophenylazo)phenyl]-1-phenylmethanone

Conditions

Conditions	Yield
Stage #1: 3-nitro-aniline With hydrogenchloride In water at 70℃; for 0.5h; Stage #2: With sodium nitrite In water at 0 - 5℃; Stage #3: 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid regioselective reaction; Further stages;	10.73 %Chromat.

Total:212 Page 1 of 6 1 2 3 4 5 6 Next>>

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Chemistry

Molecular structure of Sulisobenzone (CAS NO.4065-45-6) is:

Product Name: Sulisobenzone
CAS Registry Number: 4065-45-6
IUPAC Name: 5-benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid
Molecular Weight: 308.30648 [g/mol]
Molecular Formula: C₁₄H₁₂O₆S
XLogP3-AA: 2.2
H-Bond Donor: 2
H-Bond Acceptor: 6
EINECS: 223-772-2
Melting Point: 170 °C
Surface Tension: 59.7 dyne/cm
Density: 1.449 g/cm³
Product Categories: Industrial/Fine Chemicals;Aromatic Benzophenones & Derivatives (substituted);Organic acids

Uses

Sulisobenzone (CAS NO.4065-45-6) can be used in some sunscreens which protects the skin from damage by UVB and short-wave UVA ultraviolet light.

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
rat	LD50	oral	3530mg/kg (3530mg/kg)		Journal of the American College of Toxicology. Vol. 2(5), Pg. 35, 1983.

Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-37/39-36/37/39-27
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S27:Take off immediately all contaminated clothing.
WGK Germany: 1
RTECS: DB5044300

Specification

Sulisobenzone , its cas register number is 4065-45-6. It also can be called 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid ; 2-Benzoyl-5-methoxy-1-phenol-4-sulfonic acid ; Spectra-Sorb UV 284 ; Uvistat 1121 ; 1-Phenol-4-sulfonic acid, 2-benzoyl-5-methoxy- (6CI) ; 5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid .It is a white to yellowish powder.