CAS No.6284-40-8,D-Glucitol,1-deoxy-1-(methylamino)- Suppliers

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Basic Information

Molecular Structure:
CAS No.:	6284-40-8
Name:	D-Glucitol,1-deoxy-1-(methylamino)-
Article Data:	34
Cas Database

Formula:	C₇H₁₇NO₅
Molecular Weight:	195.216
Synonyms:	Glucitol,1-deoxy-1-(methylamino)-, D- (8CI);Sorbitol, 1-deoxy-1-methylamino- (6CI);1-Deoxy-1-(methylamino)-D-glucitol;D-(-)-N-Methylglucamine;Meglumin;Meglumine;Methylglucamin;Methylglucamine;N-Methyl-D(-)-glucamine;N-Methylglucamine;N-Methylsorbitylamine;NSC 52907;NSC 7391;
EINECS:	228-506-9
Density:	1.375 g/cm³
Melting Point:	129-131.5 °C(lit.)
Boiling Point:	490.4 °C at 760 mmHg
Flash Point:	251.6 °C
Solubility:	100 g/100 mL (25 ºC)
Appearance:	white to almost white crystalline powder
Hazard Symbols:	N/A
Risk Codes:	36/37/38
Safety:	24/25
Transport Information:	N/A
PSA:	113.18000
LogP:	-2.96740

Synthetic route

: 24758-59-6
N-methyl-D-gluconamide

: 6284-40-8
1-deoxy-1-(methylamino)-D-glucitol

Conditions

Conditions	Yield
With ammonia borane; palladium/alumina at 78℃; under 975.098 - 48004.8 Torr; for 2h; Temperature; Pressure; Reagent/catalyst; Inert atmosphere; Large scale;	69.3%

: 50-99-7
D-glucose

: 74-89-5
methylamine

: 6284-40-8
1-deoxy-1-(methylamino)-D-glucitol

Conditions

Conditions	Yield
With hydrogen In water at 10 - 100℃; under 5171.62 - 25858.1 Torr; for 21.5h;	62.5%
With nickel kieselguhr; water at 95 - 120℃; under 36775.4 - 102971 Torr; Hydrogenation;
With ethanol Hydrierung des Reaktionsprodukts an Palladium-Kohle in Methanol bei 60grad/20-25at;

: 50-99-7
D-glucose

: 6284-40-8
1-deoxy-1-(methylamino)-D-glucitol

Conditions

Conditions	Yield
With methylamine

: 50-99-7
D-glucose

: 3400-38-2
methylaminomethanol

: 6284-40-8
1-deoxy-1-(methylamino)-D-glucitol

: 557-04-0
magnesium stearate

A poloxamer: poloxamer

B: 6284-40-8
1-deoxy-1-(methylamino)-D-glucitol

: 50-99-7
D-glucose

: 74-89-5
methylamine

A: 6284-40-8
1-deoxy-1-(methylamino)-D-glucitol

B: 110-70-3
N,N`-dimethylethylenediamine

Conditions

Conditions	Yield
With 5 wt% ruthenium/carbon; hydrogen In water at 124.84℃; under 56255.6 Torr; for 1h;

...Expand

: 5-({4-[(4-butylphenyl)ethynyl]benzyl}{[2-(ethoxycarbonyl)cyclopropyl]methyl}amino)-2-fluorobenzoic acid

: 6284-40-8
1-deoxy-1-(methylamino)-D-glucitol

: 5-({4-[(4-butylphenyl)ethynyl]benzyl}{[2-(ethoxycarbonyl)cyclopropyl]methyl}amino)-2-fluorobenzoic acid N-methyl-D-glucamine salt

Conditions

Conditions	Yield
In methanol; water	100%

: gadolinium(III) oxide

: 124628-06-4
2-[1,4,7,10-tetraaza-4,7-di(1-carboxy-2-benzyloxy-ethyl)-10-carboxymethyl-cyclododecane-1-yl]-3-benzyloxypropionic acid

: 6284-40-8
1-deoxy-1-(methylamino)-D-glucitol

: {gadolinium(C8H17N4(CH2COO)(CH(COO)CH2OCH2C6H5)3)(D(-)-N-methylglucamine)}

Conditions

Conditions	Yield
In water heating to 70°C until a clear soln. was obtained; evapn. (vac.) and isolation after drying to const. weight; elem. anal.;	100%

...Expand

: gadolinium(III) oxide

: 124628-02-0
2-[1,4,7,10-tetraaza-4-(1-carboxy-2-benzyloxy-ethyl)-7,10-di(carboxymethyl)-cyclododecane-1-yl]-3-benzyloxypropionic acid

: 6284-40-8
1-deoxy-1-(methylamino)-D-glucitol

: {gadolinium(C8H17N4(CH2COO)2(CH(COO)CH2OCH2C6H5)2)(D(-)-N-methylglucamine)}

Conditions

Conditions	Yield
In water heating to 70°C until a clear soln. was obtained; evapn. (vac.) and isolation after drying to const. weight; elem. anal.;	100%

...Expand

: gadolinium(III) oxide

: 124628-08-6
2-[1,4,7,10-tetraaza-4,7,10-tri(carboxymethyl)-cyclododecane-1-yl]-3-benzyloxypropionic acid

: 6284-40-8
1-deoxy-1-(methylamino)-D-glucitol

: {gadolinium(C8H17N4(CH2COO)3CH(COO)CH2OCH2C6H5)(D(-)-N-methylglucamine)}

Conditions

Conditions	Yield
In water heating to 70°C until a clear soln. was obtained; evapn. (vac.) and isolation after drying to const. weight; elem. anal.;	100%

...Expand

Raw Materials

50-99-7

74-89-5

3400-38-2

Downstream Products

74-93-1

10225-81-7

Total:217 Page 1 of 6 1 2 3 4 5 6 Next>>

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Specification

N-Methyl-D-Glucamine , with the CAS register number 6284-40-8, is also known as 1-deoxy-1-(methylamino)-d-glucito;1-deoxy-1-(methylamino)hexitol ; glucitol, 1-deoxy-1-(methylamino)-, d- ; meglumin ; methylglucamin ; methylglucamine ; d-glucitol, 1-deoxy-1-(methylamino)- ; d(-)-n-methylglucamine .

The characteristics of this kind of chemical are as below: (1)#H bond acceptors: 6 ; (2)#H bond donors: 6 ; (3)#Freely Rotating Bonds: 11 ; (4)Polar Surface Area: 49.39 ; (5)Index of Refraction: 1.555 ; (6)Molar Refractivity: 45.58 cm³ ; (7)Molar Volume: 141.9 cm³ ; (8)Polarizability: 18.07 ×10-24cm³ ; (9)Surface Tension: 70.8 dyne/cm ; (10)Density: 1.375 g/cm³ ; (11)Flash Point: 251.6 °C ; (12)Enthalpy of Vaporization: 87.2 kJ/mol ; (13)Boiling Point: 490.4 °C at 760 mmHg ; (14)Vapour Pressure: 1.12E-11 mmHg at 25°C .

It is white to almost white crystalline powder. It is soluble in the H2O: 0.1 g/mL(clear, colorless liquid) while in the water 100 g/100 mL (25 ºC). The raw materials are acetaldehyde ammonia and 1-glucose-methylamine schiffbase . Beside, it is sensitive to air and hygroscopic.

Being a kind of irritant chemical, it is harmful to eyes, respiratory system and skin. And while using this chemical, remember to avoid contacting with skin and eyes. If you need more safety information, you could refer to the WGK Germany 3. When it comes to storing method, it should be kept under argon and in a dry place.

N-Methyl-D-Glucamine's product categories are in the below listing of anilines, aromatic amines and nitro compounds, aminosugars, biochemistry, and sugars. As for its uage, it is usualy used as the cosolvent and the surface active agent for contrast agent. We could make it as the following steps:
condense glucose and Monomethylamine and then have the catalytic hydrogenation, finally, you could get this chemical.

In addition, you could obtain the molecular structure by converting the following data information:
SMILES:O[C@H]([C@@H](O)CNC)[C@H](O)[C@H](O)CO
InChI:InChI=1/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1
InChIKey:MBBZMMPHUWSWHV-BDVNFPICBL

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