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63-42-3

Basic Information
CAS No.: 63-42-3
Name: Lactose
Molecular Structure:
Molecular Structure of 63-42-3 (Lactose)
Formula: C12H22O11
Molecular Weight: 342.3
Synonyms: 4-O-beta-D-Galactopyranosyl-D-glucose;D-Glucose, 4-O-beta-D-galactopyranosyl-;Galactinum;Fast-flo Lactose;
EINECS: 200-559-2
Density: 1.76 g/cm3
Melting Point: 222.8 °C
Boiling Point: 667.9 °C at 760 mmHg
Flash Point: 357.8 °C
Solubility: 5-10 g/100 mL at 20 °C in water
Appearance: white crystals or powder
Hazard Symbols: N/A
Risk Codes: N/A
Safety: 24/25
Transport Information: N/A
PSA: 197.37000
LogP: -5.55460
Synthetic route
492-61-5

β-D-glucose

5435-44-9, 22243-66-9

(E)-3-Ureido-but-2-enoic acid ethyl ester

63-42-3

D-(+)-lactose

Conditions
ConditionsYield
at 175℃; under 15 Torr;
64-19-7

acetic acid

41263-94-9

2’-fucosyllactose

A

2438-80-4

L-Fucose

B

63-42-3

D-(+)-lactose

492-61-5

β-D-glucose

β-D-galactose

β-D-galactose

63-42-3

D-(+)-lactose

Conditions
ConditionsYield
With zinc(II) chloride at 175℃; under 15 Torr;
3068-32-4

1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside

O2,O3;O5,O6-diisopropylidene-D-glucose-diethylacetal

O2,O3;O5,O6-diisopropylidene-D-glucose-diethylacetal

63-42-3

D-(+)-lactose

Conditions
ConditionsYield
With chloroform; iodine; silver(l) oxide anschl. mit methanol. NaOH und dann mit wss. Essigsaeure;
7647-01-0

hydrogenchloride

41263-94-9

2’-fucosyllactose

A

2438-80-4

L-Fucose

B

63-42-3

D-(+)-lactose

909878-64-4

meso-erythritol

87-69-4

L-Tartaric acid

A

488-73-3

(+)-proto-quercitol

B

57-50-1

Sucrose

C

63-42-3

D-(+)-lactose

D

pinitol

pinitol

Conditions
ConditionsYield
With oxygen for 2h; Reagent/catalyst;100%
With sodium hydroxide; palladium dichloride; potassium hexacyanoferrate(III) In water at 35℃; Rate constant; Thermodynamic data; Eact, ΔS(excit.), ΔH(excit.), ΔG(excit.);
With sodium hydroxide; potassium hexacyanoferrate(III) In water at 35℃; Rate constant; Thermodynamic data; Eact, ΔS(excit.), ΔH(excit.), ΔG(excit.);
2016-42-4

tetradecylamine

63-42-3

D-(+)-lactose

N-tetradecyl lactosamine

Conditions
ConditionsYield
at -10℃;92%
124-22-1

n-Dodecylamine

63-42-3

D-(+)-lactose

N-dodecyl lactosamine

Conditions
ConditionsYield
at -10℃;90%
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Chemistry

Molecular Structure:

Molecular Formula: C12H22O11
Molecular Weight: 342.30
IUPAC Name: (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
Synonyms of Lactose (CAS NO.200-559-2): (+)-Lactose ; 4-(beta-D-Galactosido)-D-glucose ; 4 -O-beta-D-Galactopyranosyl-D-glucose ; D-Lactose ; Lactose, anhydrous
CAS NO: 200-559-2
EINECS: 200-559-2
H bond acceptors: 11
H bond donors: 8
Freely Rotating Bonds: 12
Polar Surface Area: 101.53 Å2
Index of Refraction: 1.652
Molar Refractivity: 70.8 cm3
Molar Volume: 193.6 cm3
Surface Tension: 110.8 dyne/cm
Density: 1.76 g/cm3
Flash Point: 357.8 °C
Enthalpy of Vaporization: 112.36 kJ/mol
Boiling Point: 667.9 °C at 760 mmHg
Vapour Pressure: 1.08E-20 mmHg at 25°C
Melting Point: 222.8°C
Water Solubility: 5-10 g/100 mL at 20 ºC
Stability: Stable. Incompatible with strong oxidizing agents.
Appearance: white crystals or powder
Product Categories of  Lactose (CAS NO.200-559-2): Dextrins、Sugar & Carbohydrates

Uses

 Lactose (CAS NO.200-559-2) is used in stout beers rarely to sweeten the beer and is non-fermentable in beer.

Production

 Lactose (CAS NO.200-559-2) is little fermented by baker's yeast and during brewing, which may be used to advantage. It is extracted from sweet or sour whey.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 1500mg/kg (1500mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
rat LD50 intraperitoneal > 10gm/kg (10000mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.
rat LD50 oral > 10gm/kg (10000mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.
rat LD50 subcutaneous > 5gm/kg (5000mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

WGK Germany: 2
RTECS: OD9625000
Moderately toxic by intravenous route. Questionable carcinogen with experimental tumorigenic and teratogenic data. Mixtures with oxidants (e.g., potassium chlorate, potassium nitrate, or potassium perchlorate) may be explosion hazards. When heated to decomposition it emits acrid smoke and irritating fumes.

Specification

 Lactose is a sugar that is found most notably in milk. The name comes from the Latin word for milk, plus the -ose ending used to name sugars.