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90-80-2

Basic Information
CAS No.: 90-80-2
Name: delta-Gluconolactone
Article Data: 123
Cas Database
Molecular Structure:
Molecular Structure of 90-80-2 (delta-Gluconolactone)
Formula: C6H10O6
Molecular Weight: 178.142
Synonyms: Gluconicacid lactone (6CI);Gluconic acid, lactone, D- (7CI);Gluconic acid, d-lactone, D- (8CI);D-(+)-Gluconic acid d-lactone;D-Gluconic acid 1,5-lactone;D-Gluconic acidlactone;D-Glucono-1,5-lactone;D-Glucono-d-lactone;E 575;Fujiglucon;Gluconolactone;D-delta-Gluconolactone;Glucono-Delta-Lactone;D-Gluconic acid, d-lactone;1,5-Gluconolactone;
EINECS: 202-016-5
Density: 1.721 g/cm3
Melting Point: 151-155 °C
Boiling Point: 446.417 °C at 760 mmHg
Flash Point: 192.294 °C
Solubility: 500 g/L (20 °C) in water
Appearance: Powder
Hazard Symbols: HarmfulXn, IrritantXi
Risk Codes: 21-36/38-46-62-63
Safety: 24/25-53-36/37-26-25
Transport Information: N/A
PSA: 107.22000
LogP: -3.01320
Synthetic route
526-95-4

gluconic acid

90-80-2

D-Glucono-1,5-lactone

Conditions
ConditionsYield
In 1,4-dioxane; water for 0.183333h; microwave irradiation;92%
at 50℃; under 20 Torr;
at 70 - 80℃;
2280-44-6

D-Glucose

90-80-2

D-Glucono-1,5-lactone

Conditions
ConditionsYield
[(C4Ph4CO)(CO)2Ru]2 In cyclohexanone at 45℃; for 16h;86%
With oxygen; catalase; glucose oxidase at 25℃; Rate constant; 0.1M acetate buffer (pH=5.5);
With N-Bromosuccinimide; sulfuric acid; mercury(II) diacetate In water; acetic acid at 26.9℃; Kinetics; Thermodynamic data; Mechanism; further temperatures, also with Ru(III) as a catalyst; ΔG(excit.), ΔS(excit.), ΔH(excit.), Ea;
526-95-4

gluconic acid

A

1198-69-2

D-glucono-1,4-lactone

B

90-80-2

D-Glucono-1,5-lactone

Conditions
ConditionsYield
With water
at 78℃; under 12 Torr; beim Trocknen ueber Phosphorpentoxyd;
at 78℃; under 12 Torr; Ueber Phosphorpentoxyd;
In water at 112 - 124℃; for 2h; Sparging with nitrogen;
74421-63-9

ethyl D-gluconate

90-80-2

D-Glucono-1,5-lactone

Conditions
ConditionsYield
at 50℃; under 20 Torr;
at 70 - 80℃;
2280-44-6

D-Glucose

865-05-4

nicotinamide adenine dinucleotide

A

58-68-4

NADH

B

90-80-2

D-Glucono-1,5-lactone

Conditions
ConditionsYield
at 22℃; ph=7.0, phosphate buffer; glucose dehydrogenase;
2280-44-6

D-Glucose

A

909878-64-4

meso-erythritol

B

488-82-4

D-Arabitol

C

1198-69-2

D-glucono-1,4-lactone

D

90-80-2

D-Glucono-1,5-lactone

Conditions
ConditionsYield
With 1-methyl-pyrrolidin-2-one; Wilkinson's catalyst at 130℃; for 6h; Product distribution; Mechanism; other unprotected aldose sugars; other rhodium-catalysts; var. temp. and reaction times;
492-61-5

β-D-glucose

90-80-2

D-Glucono-1,5-lactone

Conditions
ConditionsYield
With oxygen In water Thermodynamic data; Kinetics; Mechanism; Ambient temperature; Eact, other object of study: steady state catalytic current density; condition: Redox Polymer Films Glucose oxidase/PEG/POs-EA on a vitreous-carbon-disk electrode; different conditions: air, nitrogen, different temperatures;
With glucose oxidase at 25℃; Rate constant; reductive half-reaction; also in the presence of one-elctron redox cosubstrates (differently substituted ferroceniums and promazine cation); var. pH values;
ferrocenium(III) tetrafluoroborate In water at 25℃; Rate constant; glucose oxidase from Aspergillus Niger; n-octyl-β-D-glucopyrannoside; enzymatic electrocatalysis: working electrode: glassy carbon disk, reference elektrode: SCE;
sodium D gluconate

sodium D gluconate

90-80-2

D-Glucono-1,5-lactone

Conditions
ConditionsYield
With acetic acid
50-99-7

D-glucose

water

water

7726-95-6

bromine

barium bromide

barium bromide

barium carbonate

barium carbonate

90-80-2

D-Glucono-1,5-lactone

Conditions
ConditionsYield
at 0℃; Rate constant; veschiedenen D-Glucose-Praeparate; unter Einleiten von Kohlendioxid;
50-70-4

D-sorbitol

A

2280-44-6

D-Glucose

B

6322-07-2

D-gulono-1,4-lactone

C

90-80-2

D-Glucono-1,5-lactone

Conditions
ConditionsYield
With potassium dichromate; perchloric acid In water at 33℃; Kinetics; Further Variations:; pH-values;
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    English Name: delta-Gluconolactone English synonyms: delta-Gluconolactone CAS: 90-80-2 Molecular formula: C6H10O6 Molecular weight: 178

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  • Glucono-Delta-Lactone CAS NO.90-80-2

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    Glucono-Delta-Lactone CAS NO.90-80-2

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    glucono-δ-lactone(gdl) usp26 fcciv can be used as protein coagulant, sour agent, leavening agent, preservative and used in the production of cosmetic and toothpaste. it is white crystal or crystalline powder, breaks down at about 153℃, easily

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Chemistry


Systematic Name: (3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-one (non-preferred name)
SMILES: O=C1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
InChI: InChI=1/C6H10O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-5,7-10H,1H2/t2-,3-,4+,5-/m1/s1
InChIKey: PHOQVHQSTUBQQK-SQOUGZDYBO
Empirical Formula: C6H10O6
Molecular Weight: 178.14
EINECS: 202-016-5
Product Categories: Biochemistry; Glucose; Sugar Acids; Sugars; Dextrins、Sugar & Carbohydrates 
Melting Point: 160 °C (dec.)(lit.)
alpha: 65  °(c=1,H2O)
refractive index: 63.5 ° (C=10, H2O)
Water Solubility: 500 g/L (20 °C) 
Index of Refraction: 1.607
Molar Refractivity: 35.79 cm3
Molar Volume: 103.5 cm3
Surface Tension: 98.4 dyne/cm
Density: 1.72 g/cm3
Flash Point: 192.3 °C
Enthalpy of Vaporization: 81.3 kJ/mol
Boiling Point: 446.4 °C at 760 mmHg
Vapour Pressure: 7.6E-10 mmHg at 25 °C 
Classification Code of 1,5-Gluconolactone (CAS NO.90-80-2): Chelating agent; Mutation data

Uses

 1,5-Gluconolactone (CAS NO.90-80-2) is a synergistic blend of gluconolactone and sodium benzoate. This blend provides broad spectrum protection against product spoilage in a variety of personal care formulations.

Toxicity Data With Reference

1.    

uns-mic-uns 5 mmol/L

    AMICCW    Archives of Microbiology. 109 (1976),157.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Hazard Codes: HarmfulXn,IrritantXi
Risk Statements:
R21:  Harmful in contact with skin 
R46:  May cause heritable genetic damage 
R62:  Possible risk of impaired fertility 
R63:  Possible risk of harm to the unborn child 
R36/37:  Irritating to eyes and respiratory system 
Safety Statements:
S25:  Avoid contact with eyes 
S26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
S53:  Avoid exposure - obtain special instruction before use
S24/25:  Avoid contact with skin and eyes 
S36/37:  Wear suitable protective clothing and gloves
WGK Germany: 3
RTECS: LZ5184000
F: 21
Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

Specification

  1,5-Gluconolactone (CAS NO.90-80-2), its Synonyms are D-Gluconic acid delta-lactone ; D-Gluconic acid lactone ; D-Gluconic delta-lactone ; D-Glucono-1,5-lactone ; D-delta-Gluconolactone ; Deltagluconolactone ; Gluconic acid lactone (6CI) ; Gluconic delta-lactone ; Glucono delta lactone ; Glucono delta-lactone ; Gluconolactone ; delta-Gluconolactone ; beta-Glucono-1,5-lactone .

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