- Total Synthesis of Premithramycinone H and Related Anthrapyran Antibiotics
Two approaches are described for the preparation of 2-(1',3'-dioxoalkyl)-substituted 1-hydroxyanthraquinones 10a-d and 20a-c, which were cyclized in a biomimetic-type reaction to the anthra[1,2-b]pyran skeletons 11a-d and 21a-c of the heydamcin- or pluram
- Krohn, Karsten,Vitz, Juergen
- Synthesis of homophthalates from allenic diesters: Conversion into viocristin and analogues, and application to 6-methylpretetramid
Oxy-substituted homophthalic anhydrides have been synthesized by cycloaddition of di- and tri-oxy butadienes to the allenic diester (1). By base-catalysed cycloaddition to appropriate benzoquinones they have afforded new syntheses of viocristin (19), isov
- Caliskan, Ece,Cameron, Donald W.,Griffiths, Peter G.
p. 1013 - 1020
(2007/10/03)
- Synthesis of 3-hydroxy-5-alkoxyhomophthalates by domino '2:1-coupling/intramolecular aldol condensation' reactions of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with tetraalkoxymethanes
The first domino '2:1 condensation/intramolecular aldol' reactions of 1,3-bis(trimethylsilyloxy)-1,3-butadiene with tetraalkoxymethanes provide a convenient approach to 3-hydroxy-5-alkoxyhomophthalates. These products, which contain one free and one prote
- Lubbe, Mathias,Langer, Peter
experimental part
p. 881 - 885
(2010/06/20)