- NOVEL COMPOUNDS
There is provided a compound of formula (I): processes for the manufacture thereof, pharmaceutical compositions thereof and uses in therapy.
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Page/Page column 122
(2008/06/13)
- A novel approach to functionalised 5,7,8,9-tetrahydropyrimido[4,5-b][1,4] diazepin-6-ones using intramolecular palladium-catalysed amidation
The development of a novel palladium-catalysed amidation approach towards 5,7,8,9-tetrahydropyrimido[4,5-b][1,4]diazepin-6-one templates is highlighted. The route proceeds through the reaction of an amino amide, generated by 1,4-addition of an amine to an
- Carr, Gregory R.,Feron, James L.,Johnson, Paul D.,Roberts, Craig A.,Rudge, David A.,Simpson, Iain,Wrigley, Gail L.
experimental part
p. 5049 - 5055
(2012/09/22)