- 848852-33-5
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Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent
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Bioorganic and Medicinal Chemistry Letters p. 1795 - 1801
(2011/05/11)
- File number:5
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- 848893-61-8
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Highly enantioselective and anti -diastereoselective catalytic intermolecular glyoxylate-ene reactions: Effect of the geometrical isomers of alkenes
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Organic Letters p. 2736 - 2739
(2015/06/16)
- File number:5
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- 849106-50-9
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(4-PHENYL-PIPERIDIN-1-YL)-[5-1H-PYRAZOL-4YL)-THIOPHEN-3-YL]-METHANONE COMPOUNDS AND THEIR USE
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- File number:3
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- 84911-18-2
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Nonselective bromination-selective debromination strategy: Selective bromination of unsymmetrical ketones on singly activated carbon against doubly activated carbon
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Organic Letters p. 411 - 414
(2007/10/03)
- File number:4
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- 84913-19-9
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New adamantane phenylalkylamines with σ-receptor binding affinity and anticancer activity, associated with putative antagonism of neuropathic pain
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Journal of Medicinal Chemistry p. 10241 - 10261
(2013/01/16)
- File number:11
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- 849217-47-6
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Discovery of 1,6-naphthyridinone-based MET kinase inhibitor bearing quinoline moiety as promising antitumor drug candidate
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European Journal of Medicinal Chemistry
(2020/02/29)
- File number:3
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- 849217-50-1
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A tyrosine kinase inhibitor and intermediate preparation method
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- File number:7
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- 849223-96-7
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Highly efficient carbazolyl-derived phosphine ligands: Application to sterically hindered biaryl couplings
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Chemical Communications p. 5079 - 5081
(2011/06/10)
- File number:5
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- 849353-44-2
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2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Scaffold design and advancement in HDLc-raising efficacy
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Bioorganic and Medicinal Chemistry Letters p. 1890 - 1895
(2011/05/04)
- File number:4
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- 84941-15-1
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[4+1] cyclization of benzohydrazide and ClCF2COONa towards 1,3,4-oxadiazoles and 1,3,4-oxadiazoles-d5
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Chinese Chemical Letters
(2021/09/20)
- File number:4
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- 849416-79-1
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Rh(NHC)-catalyzed direct and selective arylation of quinolines at the 8-position
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Journal of the American Chemical Society p. 3780 - 3783
(2011/05/05)
- File number:3
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- 849426-73-9
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BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF
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- File number:5
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- 849470-59-3
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(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1H-1,2, 4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid (BMS-644950): A rationally designed orally efficacious 3-hydroxy-3- methylglutaryl coenzyme-A reductase inhibitor wi
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Journal of Medicinal Chemistry p. 2722 - 2733
(2008/12/22)
- File number:4
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- 849473-02-5
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Drug to genome to drug: Discovery of new antiplasmodial compounds
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Journal of Medicinal Chemistry p. 3222 - 3240
(2011/06/27)
- File number:6
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- 84952-60-3
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Synthesis and structure-activity relationships of trisubstituted phenyl urea derivatives as neuropeptide Y5 receptor antagonists
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Journal of Medicinal Chemistry p. 2344 - 2356
(2007/10/03)
- File number:4
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- 849604-79-1
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Preparation of various carboxylic acid esters from bulky alcohols and carboxylic acids by a new type oxidation-reduction condensation using 2,6-dimethyl-1,4-benzoquinone
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Chemistry Letters p. 300 - 301
(2007/10/03)
- File number:6
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- 84964-59-0
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Gas phase generation and cyclisation reactions of some o-substituted phenyl radicals
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Tetrahedron p. 7747 - 7762
(2007/10/02)
- File number:3
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- 84964-63-6
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Synthesis of xanthones, thioxanthones, and acridones by the coupling of arynes and substituted benzoates
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Journal of Organic Chemistry p. 583 - 588
(2007/10/03)
- File number:3
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- 84969-56-2
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Superiority of the carbamoylmethyl ester as an acyl donor for the protease-catalyzed kinetically controlled peptide synthesis in organic media: Application to segment condensations
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Chemistry Letters p. 1013 - 1014
(2007/10/03)
- File number:7
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- 849777-68-0
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SN2' versus SN2 reactivity: Control of regioselectivity in conversions of Baylis-Hillman adducts
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Chemistry - A European Journal p. 1365 - 1371
(2010/06/14)
- File number:3
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- 849805-95-4
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Hitting on the move: Targeting intrinsically disordered protein states of the MDM2-p53 interaction
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European Journal of Medicinal Chemistry
(2019/08/20)
- File number:7
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- 849811-78-5
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Substrate stereocontrol in bromine-induced intermolecular cyclization: Asymmetric synthesis of pitavastatin calcium
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Tetrahedron p. 4730 - 4737
(2015/07/27)
- File number:3
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- 84994-61-6
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TRANSFORMATION OF TARTARIC ACID: A FACILE SYNTHESIS OF DERIVATIVES OF OPTICALLY ACTIVE α-HYDRXYOALDEHYDES
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Tetrahedron Letters p. 2999 - 3002
(2007/10/02)
- File number:3
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- 850008-78-5
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Chemoselective Palladium-Catalyzed Direct C–H Arylation of 5-Carboxyimidazoles: Unparalleled Access to Fused Imidazole-Based Tricycles Containing Six-, Seven- or Eight-Membered Rings
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European Journal of Organic Chemistry p. 2491 - 2494
(2017/05/12)
- File number:3
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- 850089-99-5
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Facile synthesis of 6-aryl-3-pyridyl-1,2,4-triazines as a key step toward highly fluorescent 5-substituted bipyridines and their Zn(II) and Ru(II) complexes
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Tetrahedron p. 8963 - 8973
(2008/12/22)
- File number:3
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- 85010-04-4
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Development of potent and selective inhibitors of aldo-keto reductase 1C3 (type 5 17β-hydroxysteroid dehydrogenase) based on N -phenyl-aminobenzoates and their structure-activity relationships
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Journal of Medicinal Chemistry p. 2311 - 2323
(2012/05/04)
- File number:3
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- 85014-12-6
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One-pot, regioselective synthesis of homopropargyl alcohols using pro-pargyl bromide and carbonyl compound by the mg-mediated reaction under solvent-free conditions
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Letters in Organic Chemistry p. 438 - 442
(2020/04/21)
- File number:6
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- 85020-75-3
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Bronsted acid mediated nitrogenation of propargylic alcohols: An efficient approach to alkenyl nitriles
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Organic and Biomolecular Chemistry p. 4324 - 4328
(2014/06/23)
- File number:36
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- 85020-82-2
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Reactions of a triplet arylnitrenium ion: Laser flash photolysis and product studies of N-tert-butyl(2-acetyl-4-nitrophenyl)nitrenium ion
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Journal of the American Chemical Society p. 10186 - 10193
(2007/10/03)
- File number:3
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- 85021-06-3
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REACTIONS OF BENZYNE WITH SULFIDES HAVING A CARBOXYL GROUP. A NOVEL SYNTHESIS OF ESTER AND LACTONE
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Chemistry Letters p. 1777 - 1780
(2007/10/02)
- File number:3
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- 850221-79-3
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Palladium-catalyzed cross-coupling reactions of diazine N-oxides with aryl chlorides, bromides, and iodides
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Angewandte Chemie - International Edition p. 7781 - 7786
(2007/10/03)
- File number:3
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- 850233-82-8
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Design, synthesis, and antifolate activity of new analogues of piritrexim and other diaminopyrimidine dihydrofolate reductase inhibitors with ω-carboxyalkoxy or ω-carboxy-1-alkynyl substitution in the side chain
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Journal of Medicinal Chemistry p. 4420 - 4431
(2007/10/03)
- File number:4
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- 850256-19-8
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Antiestrogen binding site and estrogen receptor mediate uptake and distribution of 4-hydroxytamoxifen-targeted doxorubicin-formaldehyde conjugate in breast cancer cells
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Journal of Medicinal Chemistry p. 6509 - 6518
(2007/10/03)
- File number:3
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- 850264-92-5
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Fluorescent molecular spring that visualizes the extension and contraction motions of a double-stranded helicate bearing terminal pyrene units triggered by release and binding of alkali metal ions
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Chemical Communications p. 12084 - 12087
(2019/10/14)
- File number:4
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- 850308-65-5
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Palladium complexes of the heterodiphosphine o- C6H 4(CH2PtBu2)(CH2PPh 2) are highly selective and robust catalysts for the hydromethoxycarbonylation of ethene
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Organometallics p. 2292 - 2305
(2010/07/04)
- File number:3
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- 850311-51-2
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Development of unsymmetrical dyads as potent noncarbohydrate-based inhibitors against human β-N-acetyl-D-hexosaminidase
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ACS Medicinal Chemistry Letters p. 527 - 531
(2013/07/26)
- File number:5
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- 850374-28-6
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Synthetic and theoretical investigation on the one-pot halogenation of β-amino alcohols and nucleophilic ring opening of aziridinium ions
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Organic and Biomolecular Chemistry p. 920 - 939
(2016/01/15)
- File number:3
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- 850424-08-7
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Design and synthesis of 6,6-fused heterocyclic amides as raf kinase inhibitors
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Bioorganic and Medicinal Chemistry Letters p. 1678 - 1681
(2012/04/04)
- File number:3
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- 850479-14-0
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XP13512 [(+/-)-1-([(alpha-isobutanoyloxyethoxy)carbonyl] aminomethyl)-1-cyclohexane acetic acid], a novel gabapentin prodrug: I. Design, synthesis, enzymatic conversion to gabapentin, and transport by intestinal solute transporters.
-
Journal of Pharmacology and Experimental Therapeutics p. 315 - 323
(2007/10/03)
- File number:5
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- 85061-28-5
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Asymmetric hydrogenation of 2-and 2,3-substituted ouinoxalines with chiral cationic ruthenium diamine catalysts
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Organic Letters p. 6568 - 6571
(2012/02/13)
- File number:4
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- 85068-38-8
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Synthesis of benzylaminopyrimidines and their fungicidal activities against wheat brown rust and barley powdery mildew
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Pesticide Science p. 223 - 229
(2007/10/03)
- File number:3
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- 850697-56-2
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Benzodiazepine calcitonin gene-related peptide (CGRP) receptor antagonists: Optimization of the 4-substituted piperidine
-
Bioorganic and Medicinal Chemistry Letters p. 5052 - 5056
(2007/10/03)
- File number:5
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- 85077-43-6
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Olefin-Oxazolines (OlefOx): Highly modular, easily tunable ligands for asymmetric catalysis
-
Angewandte Chemie - International Edition p. 1143 - 1146
(2010/05/02)
- File number:3
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- 85080-95-1
-
DETERMINATION DES SITES D'OXYDATION DES DERIVES DU α-D-GLUCOFURANOSE UTILISES COMME DONNEURS
-
Carbohydrate Research p. 25 - 32
(2007/10/02)
- File number:37
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- 850884-46-7
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A novel class of antihyperlipidemic agents with low density lipoprotein receptor up-regulation via the adaptor protein autosomal recessive hypercholesterolemia
-
Journal of Medicinal Chemistry p. 3284 - 3295
(2010/09/05)
- File number:3
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- 850895-55-5
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QSAR study for a novel series of ortho monosubstituted phenoxy analogues of α1-adrenoceptor antagonist WB4101
-
Bioorganic and Medicinal Chemistry p. 2547 - 2559
(2007/10/03)
- File number:3
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- 850895-65-7
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QSAR study for a novel series of ortho monosubstituted phenoxy analogues of α1-adrenoceptor antagonist WB4101
-
Bioorganic and Medicinal Chemistry p. 2547 - 2559
(2007/10/03)
- File number:4
-
- 850-92-0
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Catalytic asymmetric torgov cyclization: A concise total synthesis of (+)-estrone
-
Angewandte Chemie - International Edition p. 8770 - 8773
(2014/08/18)
- File number:4
-
- 85093-02-3
-
An Improved Method for the Preparation of 2,5-Disubstituted Thiophenes
-
Synthesis p. 1061 - 1062
(2007/10/02)
- File number:4
-