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All total 9 Articles be found
All total 9 Articles be foundPhotocatalytic Carboxylation of Phenyl Halides with CO2 by Metal-Organic Frameworks Materials
Han, Jianyu,Qiu, Xueying,Su, Lina,Tang, Zhiyong,Zhang, Yin
, p. 312 - 316 (2021/01/04)
In this work, important commercial pharmaceutical intermediates, phenylpropionic acid compounds, are successfully obtained by catalyzing the reaction of carbon dioxide with phenyl halides using MOF-5, a typical metal-organic framework (MOF) material. The influence of temperature, pressure, catalyst type and light on the reaction is investigated, and a 90.3% selectivity towards fluorophenylpropionic acid is reached. Significantly, the catalysts are effective for varied benzyl compounds containing different substituent groups. The catalysts are stable and remain active after three cycles.
Macrolactam Synthesis via Ring-Closing Alkene-Alkene Cross-Coupling Reactions
Goh, Jeffrey,Loh, Teck-Peng,Maraswami, Manikantha
supporting information, p. 9724 - 9728 (2020/12/21)
Reported herein is a practical method for macrolactam synthesis via a Rh(III)-catalyzed ring closing alkene-alkene cross-coupling reaction. The reaction proceeded via a Rh-catalyzed alkenyl sp2 C-H activation process, which allows access to macrocyclic molecules of different ring sizes. Macrolactams containing a conjugated diene framework could be easily prepared in high chemoselectivities and Z,E stereoselectivities.
INHIBITORS OF FUNGAL INVASION
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Drawing sheet 78, (2010/02/09)
This invention relates to various anti-fungall agents including agents that are inhibitors of fungal invasion.
Effect of deuterated solvents toward 2,2,2-trichloroethyl esters with a benzylic methylene moiety
Mineno, Tomoko,Hirayama, Haruyasu,Nakahara, Kazuhide,Yamashita, Mitsuaki,Kansui, Hisao,Moriwaki, Hiroshi
experimental part, p. 6045 - 6048 (2010/11/21)
The indium-promoted chemoselective deprotection of 2,2,2-trichloroethyl esters containing a benzylic methylene was successfully achieved by employing deuterated solvents.
A General, Activator-Free Palladium-Catalyzed Synthesis of Arylacetic and Benzoic Acids from Formic Acid
Wang, Lin,Neumann, Helfried,Beller, Matthias
supporting information, p. 6910 - 6914 (2018/06/04)
A new catalyst for the carboxylative synthesis of arylacetic and benzoic acids using formic acid (HCOOH) as the CO surrogate was developed. In an improvement over previous work, CO is generated in situ without the need for any additional activators. Key to success was the use of a specific system consisting of palladium acetate and 1,2-bis((tert-butyl(2-pyridinyl)phosphinyl)methyl)benzene. The generality of this method is demonstrated by the synthesis of more than 30 carboxylic acids, including non-steroidal anti-inflammatory drugs (NSAIDs), under mild conditions in good yields.
