The Acetamide,2,2,2-trifluoro-N-(2-hydroxyethyl)-, with the CAS registry number 6974-29-4, is also known as N-(2-Hydroxyethyl)trifluoroacetamide. This chemical's molecular formula is C₄H₆F₃NO₂ and molecular weight is 157.09. What's more, its systematic name is 2,2,2-Trifluoro-N-(2-hydroxyethyl)acetamide. The product should be sealed and stored in cool and dry places and it should be ensured that the workshop is well ventilated. In addition, it needs to be protected from strong oxidizers, bases, acids and reducing agents.

Physical properties of Acetamide,2,2,2-trifluoro-N-(2-hydroxyethyl)- are: (1)ACD/LogP: -0.42; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.42; (4)ACD/LogD (pH 7.4): -0.42; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 14.11; (8)ACD/KOC (pH 7.4): 14.1; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 29.54 Å²; (13)Index of Refraction: 1.375; (14)Molar Refractivity: 26.19 cm³; (15)Molar Volume: 114.3 cm³; (16)Polarizability: 10.38×10^-24 cm³; (17)Surface Tension: 28.6 dyne/cm; (18)Density: 1.373 g/cm³; (19)Flash Point: 95.8 °C; (20)Enthalpy of Vaporization: 54.8 kJ/mol; (21)Boiling Point: 234.7 °C at 760 mmHg; (22)Vapour Pressure: 0.00953 mmHg at 25°C.

Preparation: this chemical can be prepared by 2-amino-ethanol and trifluoroacetic acid methyl ester at the ambient temperature. This reaction will need solvent diethyl ether with the reaction time of 3 hours and the yield is about 65%.

Uses of Acetamide,2,2,2-trifluoro-N-(2-hydroxyethyl)-: it can be used to produce 2-[N-(2,2,2-trifluoroacetyl)amino]ethyl phosphordichloridite. It will need reagent PCl₃ and solvent acetonitrile with the reaction time of 3 hours. The yield is about 87%.

When you are using this chemical, please be cautious about it as the following:
It is harmful by inhalation, in contact with skin and if swallowed and it is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing.

You can still convert the following datas into molecular structure:
(1)SMILES: FC(F)(F)C(=O)NCCO
(2)InChI: InChI=1S/C4H6F3NO2/c5-4(6,7)3(10)8-1-2-9/h9H,1-2H2,(H,8,10)
(3)InChIKey: NPSVCXHBJVBBAD-UHFFFAOYSA-N