Welcome to LookChem.com Sign InJoin Free

Product Database

4H-1-Benzopyran-4-one,5-hydroxy-7- methoxy-2-(3,4,5-trimethoxyphenyl)-

Basic information
MSDS
Article
Preparation methods
Raw materials And Target Products

Home > CAS database list > 4H-1-Benzopyran-4-one,5-hydroxy-7- methoxy-2-(3,4,5-trimethoxyphenyl)-

Basic informationMSDSArticlePreparation methodsRaw materials And Target ProductsPost Buying Request Now

4H-1-Benzopyran-4-one,5-hydroxy-7- methoxy-2-(3,4,5-trimethoxyphenyl)-

CAS Number:18103-41-8
Molecular Formula:C19H18O7
Molecular Weight:358.348
Mol File:18103-41-8.mol

Synonyms:5-hydroxy-3',4',5',7-tetramethoxyflavone;5-Hydroxy-7-methoxy-2-(3,4,5-trimethoxy-phenyl)-chromen-4-on;5-Hydroxy-7-methoxy-2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one;corymbosin;5-hydroxy-7-methoxy-2-(3,4,5-trimethoxy-phenyl)-chromen-4-one;Miricetin-3,7,3',4'-tetramethylaether;

Physicochemical Properties

Melting Point:N/A
Boiling Point:561.1±50.0 °C(Predicted)
Density:1.309±0.06 g/cm3(Predicted)
Solubility:N/A
Flash Point:N/A
Vapor Density:N/A
Refractive Index:N/A
Sensitive:N/A
Storage Temp.:N/A
Appearance/Colour:N/A

Pictogram(s):

Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Precautionary statement(s)
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Chemical name	Common names and synonyms	CAS number	EC number	Concentration
5-hydroxy-7-methoxy-2-(3',4',5'-trimethoxyphenyl)-4H-chromen-4-one	5-hydroxy-7-methoxy-2-(3',4',5'-trimethoxyphenyl)-4H-chromen-4-one	18103-41-8	none	100%

4H-1-Benzopyran-4-one,5-hydroxy-7- methoxy-2-(3,4,5-trimethoxyphenyl)- Relevant articlesAll total 5 Articles be found

DOWNLOAD

Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs

-

Page/Page column 71, (2017/07/01)

Disclosed is a use of flavones derivatives and flavanone derivatives in preparation of sedative and hypnotic drugs.

DOWNLOAD

The Preparation of Flavones and their Derivatives. Part I. Flavones and 4-Thioflavones.

Briggs, Malcolm T.,Duncan, Graham L. S.,Thornber, Craig W.

, p. 2461 - 2487 (2007/10/02)

A series of polysubstituted flavones has been prepared with particular emphasis on 3',4',5',5,7-pentahydroxyflavone and its ether derivatives.The preparation of 4-thioflavones has been undertaken to provide intermediates for the preparation of 4-iminoflav

DOWNLOAD

Synthesis of novel flavonoid derivatives as potential HIV-integrase inhibitors

Mateeva, Nelly N.,Kode, Rao N.,Redda, Kinfe K.

, p. 1251 - 1258 (2007/10/03)

Eighteen novel flavonoid derivatives - substituted chalcones and flavones were synthesized and characterized by using NMR, IR, UV/Vis spectroscopy and elemental analysis. The target compounds were achieved by using a sequence of simple and effective reactions starting from phloroglucinol. The initial hydroxyl groups were protected by methylation and in the final flavones the 5-OH group was selectively demethylated by means of AlBr3. 5-methoxy flavones exhibit a strong fluorescence, which was quenched after the removal of the methyl group.

DOWNLOAD

Synthesis of Benzopyran-Fused Flavone Derivatives via Microwave-Assisted Intramolecular C-H Activation

Sipos, Zoltán,Kónya, Krisztina

, p. 1610 - 1620 (2018/03/21)

A microwave-assisted intramolecular direct arylation method for the synthesis of benzopyran-fused flavone derivatives containing natural flavone backbones is described. Different polyalkoxy flavones were synthesized and functionalized with 2-bromobenzyl bromide. The resulting compounds were subjected to palladium-catalyzed intramolecular direct arylation reactions supported by microwave irradiation to produce fused tetracyclic flavones. In the case of the 7-substituted chrysin derivative, the regioselectivity of the coupling was also examined.

DOWNLOAD

Synthesis and Characterization of Ruthenium(II) Complexes of 5-Hydroxyflavones

Silva, Artur M. S.,Cavaleiro, Jose A. S.,Tarrago, Georges,Marzin, Claude

, p. 97 - 104 (2007/10/02)

Bis(dimethyl sulfoxide)bis(flavonato)ruthenium(II) complexes, RuL2(DMSO)2, were synthesized by the reaction of dichlorotetrakis(dimethyl sulfoxide)ruthenium(II) with the sodium salts of 5-hydroxyflavone, 5-hydroxy-4'-methoxyflavone, and 5-hydroxy-3',4',5'

4H-1-Benzopyran-4-one,5-hydroxy-7- methoxy-2-(3,4,5-trimethoxyphenyl)- Synthetic route And Reaction conditions

: 53350-26-8
5,7-Dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one

: 18103-41-8
5-hydroxy-7-methoxy-2-(3',4',5'-trimethoxyphenyl)-4H-chromen-4-one

Conditions

Conditions	Yield
Withaluminum (III) chloride;Inacetonitrile;at 0 ℃; Inert atmosphere; Reflux;	77%
Withaluminium trichloride;Inacetonitrile;for 4h; Heating;	49%
Withaluminum tri-bromide;Inacetonitrile;at 20 ℃; for 5h;	20%

: 77-78-1
dimethyl sulfate

: 18103-41-8
5-hydroxy-7-methoxy-2-(3',4',5'-trimethoxyphenyl)-4H-chromen-4-one

Conditions

Conditions	Yield
Withpotassium carbonate; acetone;

: 90-24-4
2-hydroxy-4,6-dimethoxyacetophenone

: 18103-41-8
5-hydroxy-7-methoxy-2-(3',4',5'-trimethoxyphenyl)-4H-chromen-4-one

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: pyridine / 12 h / 70 - 75 °C / Heating 1.2: powdered KOH / pyridine / 5 h / 60 - 70 °C 1.3: 50 percent / cc. H₂SO₄ / acetic acid / 5 h / 60 - 70 °C / Heating 2.1: 20 percent / AlBr₃ / acetonitrile / 5 h / 20 °C Withaluminum tri-bromide;Inpyridine; acetonitrile;1.1: Baker-Venkataraman synthesis;
Multi-step reaction with 3 steps 1: potassium hydroxide / ethanol; water / 0 - 20 °C 2: iodine / dimethyl sulfoxide / Reflux 3: aluminum (III) chloride / acetonitrile / 0 °C / Inert atmosphere; Reflux Withaluminum (III) chloride; iodine; potassium hydroxide;Inethanol; water; dimethyl sulfoxide; acetonitrile;1: \|Claisen-Schmidt Condensation;

: 108-73-6
3,5-dihydroxyphenol

: 18103-41-8
5-hydroxy-7-methoxy-2-(3',4',5'-trimethoxyphenyl)-4H-chromen-4-one

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: BF₃Et₂O 2.1: anhydr. K₂CO₃ / acetone / 0.5 h / 50 - 60 °C 3.1: pyridine / 12 h / 70 - 75 °C / Heating 3.2: powdered KOH / pyridine / 5 h / 60 - 70 °C 3.3: 50 percent / cc. H₂SO₄ / acetic acid / 5 h / 60 - 70 °C / Heating 4.1: 20 percent / AlBr₃ / acetonitrile / 5 h / 20 °C With*aluminum tri-bromide; boron trifluoride diethyl etherate; potassium carbonate;Inpyridine; acetone; acetonitrile;3.1: Baker-Venkataraman synthesis;

Yield

Multi-step reaction with 4 steps

1.1: BF₃*Et₂O

2.1: anhydr. K₂CO₃ / acetone / 0.5 h / 50 - 60 °C

3.1: pyridine / 12 h / 70 - 75 °C / Heating

3.2: powdered KOH / pyridine / 5 h / 60 - 70 °C

3.3: 50 percent / cc. H₂SO₄ / acetic acid / 5 h / 60 - 70 °C / Heating

4.1: 20 percent / AlBr₃ / acetonitrile / 5 h / 20 °C

Withaluminum tri-bromide; boron trifluoride diethyl etherate; potassium carbonate;Inpyridine; acetone; acetonitrile;3.1: Baker-Venkataraman synthesis;

: 480-66-0,67471-34-5
2,4,6-trihydroxyacetophenone

: 18103-41-8
5-hydroxy-7-methoxy-2-(3',4',5'-trimethoxyphenyl)-4H-chromen-4-one

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: anhydr. K₂CO₃ / acetone / 0.5 h / 50 - 60 °C 2.1: pyridine / 12 h / 70 - 75 °C / Heating 2.2: powdered KOH / pyridine / 5 h / 60 - 70 °C 2.3: 50 percent / cc. H₂SO₄ / acetic acid / 5 h / 60 - 70 °C / Heating 3.1: 20 percent / AlBr₃ / acetonitrile / 5 h / 20 °C Withaluminum tri-bromide; potassium carbonate;Inpyridine; acetone; acetonitrile;2.1: Baker-Venkataraman synthesis;
Multi-step reaction with 2 steps 1: sodium-<3,4,5-trimethoxy benzoate> / 175 °C / anschliessend Erwaermen mit wss.-aethanol. Kalilauge und Erwaermen des Reaktionsprodukts mit Essigsaeure 2: potassium carbonate Withsodium 3,4,5-trimethoxybenzoate; potassium carbonate;
Multi-step reaction with 4 steps 1: potassium carbonate / acetone / 5 h / Reflux 2: potassium hydroxide / ethanol; water / 0 - 20 °C 3: iodine / dimethyl sulfoxide / Reflux 4: aluminum (III) chloride / acetonitrile / 0 °C / Inert atmosphere; Reflux Withaluminum (III) chloride; iodine; potassium carbonate; potassium hydroxide;Inethanol; water; dimethyl sulfoxide; acetone; acetonitrile;2: \|Claisen-Schmidt Condensation;

: 1719-88-6
3,4,5-trimethoxybenzoic anhydride

: 18103-41-8
5-hydroxy-7-methoxy-2-(3',4',5'-trimethoxyphenyl)-4H-chromen-4-one

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium-<3,4,5-trimethoxy benzoate> / 175 °C / anschliessend Erwaermen mit wss.-aethanol. Kalilauge und Erwaermen des Reaktionsprodukts mit Essigsaeure 2: potassium carbonate Withsodium 3,4,5-trimethoxybenzoate; potassium carbonate;

: 18103-42-9
5,7-dihydroxy-3',4',5'-trimethoxyflavone

: 77-78-1
dimethyl sulfate

: 18103-41-8
5-hydroxy-7-methoxy-2-(3',4',5'-trimethoxyphenyl)-4H-chromen-4-one

Conditions

Conditions	Yield
Withpotassium carbonate;

: 53350-27-9
(E)-1-(2′-hydroxy-4′,6′-dimethoxyphenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one

: 18103-41-8
5-hydroxy-7-methoxy-2-(3',4',5'-trimethoxyphenyl)-4H-chromen-4-one

Conditions

Conditions	Yield
Withhydrogenchloride; aluminium trichloride; iodine;Yield given. Multistep reaction;
Multi-step reaction with 2 steps 1: iodine / dimethyl sulfoxide / Reflux 2: aluminum (III) chloride / acetonitrile / 0 °C / Inert atmosphere; Reflux Withaluminum (III) chloride; iodine;Indimethyl sulfoxide; acetonitrile;

: 18103-41-8
5-hydroxy-7-methoxy-2-(3',4',5'-trimethoxyphenyl)-4H-chromen-4-one

Conditions

Conditions	Yield

: 18103-41-8
5-hydroxy-7-methoxy-2-(3',4',5'-trimethoxyphenyl)-4H-chromen-4-one

: 3433-80-5
1-Bromo-2-bromomethyl-benzene

: 11-methoxy-2-(3,4,5-trimethoxyphenyl)-4H,6H-benzo[c]pyrano[2,3-h]chromen-4-one

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: potassium carbonate / N,N-dimethyl-formamide / 20 °C 2: palladium diacetate; triphenylphosphine; Trimethylacetic acid; potassium phosphate / N,N-dimethyl-formamide / 1 h / 120 °C / Microwave irradiation; Inert atmosphere; Sealed tube Withpotassium phosphate; palladium diacetate; potassium carbonate; triphenylphosphine; Trimethylacetic acid;InN,N-dimethyl-formamide;

Yield

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 20 °C

2: palladium diacetate; triphenylphosphine; Trimethylacetic acid; potassium phosphate / N,N-dimethyl-formamide / 1 h / 120 °C / Microwave irradiation; Inert atmosphere; Sealed tube

Withpotassium phosphate; palladium diacetate; potassium carbonate; triphenylphosphine; Trimethylacetic acid;InN,N-dimethyl-formamide;

Business Type:: Lab/Research institutionsTrading CompanyManufacturers

Certificate:: Product LicenseEnterprise AuthenticationISOGMPFDAHALAL

Country :: China (Mainland)(1)

4H-1-Benzopyran-4-one,5-hydroxy-7- methoxy-2-(3,4,5-trimethoxyphenyl)- suppliers

Hebei Nengqian import and export trade Co., Ltd

Cas No: 18103-41-8Product Name:5-hydroxy-3',4',5',7-tetramethoxyflavone CAS 18103-41-8Purity:Pharmaceutical grade,Min.Order: 1 GramFOB Price: USD $ 50.0-110.0 / GramPayment Terms:L/C,D/A,D/P,T/T,Western Union,MoneyGram,OtherPort:port of Qingdao、port of TianjinAvailable Specifications:In plastic outside weave or according to your request

Company profile:

Mi compa?ía profesional de procesamiento de materias primas, productos químicos, medicamentos de venta en UN intermediario, medicina veterinaria, tintes, pigmentos, UN maquillaje materiales y reactivos químicos, me posee equipos de ventas, servicio y vertical de información de una sólida red de marketing, producto vendible y YuanXiao de asia, europa, áfrica, y más de 20 países y regiones.Empresas el concepto de "persecución de calidad, innovación y desarrollo", basada en los servicios, la calidad para sobrevivir, para el desarrollo tecnológico, insiste en la oración a los usuarios de productos, precios de sorpresa a los usuarios, permite a los usuarios de servicios de concepción, en el desarrollo futuro, provincia de hebei que contará siempre con la "innovación, integridad del concepto, lograr la integridad, en el camino de especialización, la internacionalización, ?Sigue adelante!

Contact Supplier Now

Total:1 Page 1 of 1 1

Please post your buying leads,so that our qualified suppliers will soon contact you!

*Required Fields

Post Buying Request Now

[Hangzhou]86-571-87562588,87562561,87562573Our Legal adviser: Lawyer

Product Database

4H-1-Benzopyran-4-one,5-hydroxy-7- methoxy-2-(3,4,5-trimethoxyphenyl)-

4H-1-Benzopyran-4-one,5-hydroxy-7- methoxy-2-(3,4,5-trimethoxyphenyl)-

Physicochemical Properties

4H-1-Benzopyran-4-one,5-hydroxy-7- methoxy-2-(3,4,5-trimethoxyphenyl)- Safety information and MSDS

·Hazard identification:

·Composition/information on ingredients:

·First-aid measures:

·Fire-fighting measures:

·Accidental release measures:

4H-1-Benzopyran-4-one,5-hydroxy-7- methoxy-2-(3,4,5-trimethoxyphenyl)- Relevant articlesAll total 5 Articles be found