- CAS Number:10160-87-9
- Molecular Formula:C7H12O2
- Molecular Weight:128.171
- Mol File:10160-87-9.mol
Synonyms:Propiolaldehyde diethyl acetal;Propyne, 3,3-diethoxy-;1,1-Diethoxyprop-2-yne;2-Propyn-1-al diethyl acetal;3,3-Diethoxy-1-propyne;3,3-Diethoxypropyne;NSC 45019;Propynaldiethyl acetal;
- Melting Point:N/A
- Boiling Point:139 °C at 760 mmHg
- Density:0.909 g/cm3
- Flash Point:32.2 °C
- Vapor Density:N/A
- Refractive Index:n20/D 1.412(lit.)
- Storage Temp.:2-8°C
- Appearance/Colour:Clear light yellow liquid
1-Propyne,3,3-diethoxy- Safety information and MSDS
H226 Flammable liquid and vapour
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264 Wash ... thoroughly after handling.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].
P370+P378 In case of fire: Use ... to extinguish.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P313 If skin irritation occurs: Get medical advice/attention.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313 If eye irritation persists: Get medical advice/attention.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P312 Call a POISON CENTER/doctor/…if you feel unwell.
P403+P235 Store in a well-ventilated place. Keep cool.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to ...
·Composition/information on ingredients:
|Chemical name||Common names and synonyms||CAS number||EC number||Concentration|
|Propargylaldehyde Diethyl Acetal||Propargylaldehyde Diethyl Acetal||10160-87-9||none||100%|
General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.
·Accidental release measures:
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.
1-Propyne,3,3-diethoxy- Relevant articlesAll total 10 Articles be found
Versatile methodology to synthesize oxygen-bridged nine- and ten-membered cycloalkanes by the hypoiodite reaction
Montana, Angel M.,Ponzano, Stefano,Kociok-Koehn, Gabriele,Font-Bardia, Merce,Solans, Xavier
, p. 4383 - 4401 (2008/04/13)
C-3 derivatives of 6-hydroxy-2,7-dimethyl-11-oxatricyclo[220.127.116.11 2,6]undecan-4-one reacted with lead tetraacetate (LTA) and iodine to afford, in good yield, 1,7-epoxycyclononanes, which are the result of a β-fragmentation of the C2-C6 bond adjacent to the tertiary hydroxy group on C-6. This β-fragmentation is followed by a ring contraction from a ten- to a nine-membered ring system, by a free-radical addition to the carbonyl group on C-4. The reaction of precursors (not functionalized on C-3) with LTA and iodine produced a β-fragmentation without any further structural rearrangement, affording 1,8-epoxycyclodecanes. The transformation of the carbonyl group on C-4 to acetate avoided radical additions and rearrangements affording, in high yield, the corresponding cyclodecanes. By this methodology, either 1,7-epoxycyclononane or 1,8-epoxycyclodecane could be synthesized, in good yield, by choosing the appropriate substitution pattern on C-3 in the substrate. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.
Sequential and tandem oxidation/acetalization procedures for the direct generation of acetals from alcohols
Smith, Brendan M.,Graham, Andrew E.
, p. 4891 - 4894 (2008/02/08)
Alcohols are transformed directly into either acyclic or cyclic acetals in both tandem and sequential oxidation/acetalization processes using manganese dioxide, trialkyl orthoformates and catalytic quantities of indium triflate.
Quantitative production of butenes from biomass-derived γ-valerolactone catalysed by hetero-atomic MFI zeolite
Lin, Longfei,Sheveleva, Alena M.,da Silva, Ivan,Parlett, Christopher M. A.,Tang, Zhimou,Liu, Yueming,Fan, Mengtian,Han, Xue,Carter, Joseph H.,Tuna, Floriana,McInnes, Eric J. L.,Cheng, Yongqiang,Daemen, Luke L.,Rudi?, Svemir,Ramirez-Cuesta, Anibal J.,Tang, Chiu C.,Yang, Sihai
, p. 86 - 93 (2019/12/30)
The efficient production of light olefins from renewable biomass is a vital and challenging target to achieve future sustainable chemical processes. Here we report a hetero-atomic MFI-type zeolite (NbAlS-1), over which aqueous solutions of γ-valerolactone (GVL), obtained from biomass-derived carbohydrates, can be quantitatively converted into butenes with a yield of >99% at ambient pressure under continuous flow conditions. NbAlS-1 incorporates simultaneously niobium(v) and aluminium(iii) centres into the framework and thus has a desirable distribution of Lewis and Br?nsted acid sites with optimal strength. Synchrotron X-ray diffraction and absorption spectroscopy show that there is cooperativity between Nb(v) and the Br?nsted acid sites on the confined adsorption of GVL, whereas the catalytic mechanism for the conversion of the confined GVL into butenes is revealed by in situ inelastic neutron scattering, coupled with modelling. This study offers a prospect for the sustainable production of butene as a platform chemical for the manufacture of renewable materials.
Propynal equivalents and diazopropyne: Synthesis of all mono-13C isotopomers
Seburg, Randal A.,Hodges, Jonathan A.,McMahon, Robert J.
experimental part, p. 1626 - 1643 (2009/10/17)
Mechanistic and spectroscopic investigations of reactive C 3H2 hydrocarbons necessitated the preparation of diazopropyne isotopomers bearing mono-13C substitution at each of the three unique positions. The diazo compounds and their tosylhydrazone precursors were prepared from the mono-13C isotopomers of propynal (in the form of either the aldehyde or the diethyl acetal). The introduction of 13C-labeling at either alkyne position in propynal utilized the Corey - Fuchs procedure for chain homologation.
Method for synthesizing bis(2-methyl-3-furyl) disulfide
Paragraph 0057; 0061-0064; 0081; 0089-0094; 0115; 0119-0122, (2017/07/19)
The invention relates to a method for synthesizing bis(2-methyl-3-furyl) disulfide. The method comprises the following steps: (1) enabling acrolein to react with bromine to obtain a product 1; (2) adding the product 1 into an absolute ethyl alcohol solution of sodium hydroxide to prepare propiolaldehyde diethyl acetal; (3) enabling ethyl ether and bromoethane to react with chloroethane in presence of magnesium, then adding mixed liquid of the propiolaldehyde diethyl acetal and the ethyl ether and subsequently adding mixed liquid of acetaldehyde and ethyl ether for carrying out a reaction, and hydrolyzing to prepare 4-hydroxy-2-pentyne propanal diethyl acetal; (4) adding the 4-hydroxy-2-pentyne propanal diethyl acetal into a water solution containing sulfuric acid, pentane and potassium thiocyanate to prepare a product 4; (5) adding the product 4 into a sodium hydroxide water solution to prepare the bis(2-methyl-3-furyl) disulfide. Compared with the existing synthesis method, the method provided by the invention is easy in control of reaction conditions, fewer in side reactions, easy in control of intermediate products and higher in yield of a target product, thus having wide application prospect.
1-Propyne,3,3-diethoxy- Synthetic route And Reaction conditions
Withsodium hydroxide; at 160 ℃;
orthoformic acid triethyl ester
Withpotassium tert-butylate; tert-butyl alcohol; at 100 ℃;
at 150 ℃; under 20 Torr;
Withpotassium hydroxide;tetraoctyl ammonium bromide;InPetroleum ether;at 80 ℃; for 6h;
Withammonia; sodium amide;Indiethyl ether;at -34 ℃; for 0.25h;
Withammonia; sodium amide; at -30 ℃;
Withpotassium hydroxide;tetraoctyl ammonium bromide;Incyclohexane;Heating;
Withammonia; sodium amide;
Withsodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate;Inethanol; water;at 20 ℃;
orthoformic acid triethyl ester
Multistep reaction; (i) (bromination), (ii) /BRN= 605384/, (iii) NaNH2, liq. NH3;
1-Propyne,3,3-diethoxy- Raw materials
1-Propyne,3,3-diethoxy- Target Products
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