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10217-52-4

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Basic Information
CAS No.: 10217-52-4
Name: Hydrazine hydrate
Molecular Structure:
Molecular Structure of 10217-52-4 (Hydrazine hydrate)
Formula: H4N2.H2O
Molecular Weight: 50.06
Synonyms: Hydrazine,hydrate (6CI,7CI);Hydrazine, monohydrate (8CI,9CI);Hydrazinium hydroxide;Hydrazine, hydrate(1:1);
EINECS: 206-114-9
Density: 1.032 g/cm3
Melting Point: -51.5 °C
Boiling Point: 113.5 °C at 760 mmHg
Flash Point: 204°F
Solubility: miscible with water
Appearance: colorless fuming liquid
Hazard Symbols: ToxicT,DangerousN
Risk Codes: 45-20/21/22-34-43-51/53-50/53-23/24/25
Safety: 53-45-60-61-36/37/39-26
Transport Information: UN 2029/2030
PSA: 61.27000
LogP: 0.15510
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    low price\high quality\64%\hydrazine hydrate

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    Low price, high quality hyrazine hydrate, 64%concentration. Export to many countries. Appearance:Clear and colorless liquid Application:Hydrazine hydrate is widely used as a reducing agent or an intermediate of synthesis in various industrial sect

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Specification

The IUPAC name of this chemical is hydrazine hydrate. With the CAS registry number 10217-52-4, it is also named as diazanium, hydroxide (1:1). The product's categories are Pharmaceutical Intermediates; Chemistry. It is colorless fuming liquid which is miscible with water and ethanol, insoluble in chloroform and ether. Additionally, this chemical has strong reduction and corrosion. This material and its container must be disposed of as hazardous waste. So people should avoid release it to the environment.

The other characteristics of this product can be summarized as: (1)ACD/LogP: -1.20; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -3.73; (4)ACD/LogD (pH 7.4): -2.04; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)#H bond acceptors: 2; (8)#H bond donors: 4; (9)#Freely Rotating Bonds: 1; (10)Polar Surface Area: 6.48 Å2; (11)Enthalpy of Vaporization: 41.8 kJ/mol; (12)Boiling Point: 113.5 °C at 760 mmHg; (13)Vapour Pressure: 20.7 mmHg at 25°C; (14)Exact Mass: 50.048013; (15)MonoIsotopic Mass: 50.048013; (16)Topological Polar Surface Area: 53; (17)Heavy Atom Count: 3.

Preparation of Hydrazine, hydrate(1:1): It can be obtained by the following reaction. NH2CONH2+NaOCl+2NaOH→H2N—NH2·H2O+NaCl+Na2CO3

Uses of Hydrazine, hydrate(1:1): It can be used in organic synthesis. And it is also used as reducing agent and solvent. In addition, this chemical is used as oxygen scavenger in boiler water treatment system.

When you are using this chemical, please be cautious about it as the following:
It is not only harmful by inhalation, in contact with skin and if swallowed, but also toxic by inhalation, in contact with skin and if swallowed. And it also can cause burns. Furthermore, Hydrazine, hydrate(1:1) is very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) Avoid exposure - obtain special instructions before use.

People can use the following data to convert to the molecule structure.
1. SMILES:O.NN
2. InChI:InChI=1/H4N2.H2O/c1-2;/h1-2H2;1H2

The following are the toxicity data which has been tested.

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rabbit LDLo skin 20mg/kg (20mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LIVER: FATTY LIVER DEGERATION

KIDNEY, URETER, AND BLADDER: PROTEINURIS
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 4(8), Pg. 27, 1960.
rabbit LDLo subcutaneous 10mg/kg (10mg/kg) BEHAVIORAL: FOOD INTAKE (ANIMAL)

KIDNEY, URETER, AND BLADDER: PROTEINURIS

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 4(8), Pg. 27, 1960.
rat LCLo inhalation 10ug/m3/2H (0.01mg/m3) LIVER: FATTY LIVER DEGERATION

KIDNEY, URETER, AND BLADDER: PROTEINURIS

BLOOD: NORMOCYTIC ANEMIA
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 4(8), Pg. 27, 1960.
rat LDLo skin 70mg/kg (70mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

LIVER: FATTY LIVER DEGERATION

BLOOD: HEMORRHAGE
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 5(10), Pg. 48, 1961.
rat LDLo subcutaneous 50mg/kg (50mg/kg) LIVER: FATTY LIVER DEGERATION

KIDNEY, URETER, AND BLADDER: PROTEINURIS

BLOOD: NORMOCYTIC ANEMIA
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 4(8), Pg. 27, 1960.