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Cas Database

4354-73-8

4354-73-8

Identification

  • Molecular Formula:C9N10N2

  • EINECS:

Synonyms:MALONONITRILE,CYCLOHEXYLIDENE;Propanedinitrile,cyclohexylidene;2-cyclohexylidenmalononitrile;cyclohexylidenepropanedinitrile;2-cyclohexylidene malononitrile;(cyclohexylidene)malononitrile;cyclohexylidenemalonodinitrile;

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Safety information and MSDS

  • Pictogram(s):A poison.

  • Hazard Codes:A poison.

  • Signal Word:

  • Hazard Statement:

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price

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  • Manufacture/Brand:Acints
  • Product Description:2-Cyclohexylidene-malononitrile 95%+
  • Packaging:500mg
  • Price:$ 137.75
  • Delivery:In stock
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  • Manufacture/Brand:Acints
  • Product Description:2-Cyclohexylidene-malononitrile 95%+
  • Packaging:5g
  • Price:$ 717.75
  • Delivery:In stock
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  • Manufacture/Brand:Advanced Chemicals Intermediatesced Chemicals Intermediates
  • Product Description:2-Cyclohexylidene-malononitrile 95%+
  • Packaging:500mg
  • Price:$ 137.75
  • Delivery:In stock
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  • Manufacture/Brand:AK Scientific
  • Product Description:2-Cyclohexylidenemalononitrile
  • Packaging:1g
  • Price:$ 150
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  • Manufacture/Brand:AK Scientific
  • Product Description:2-Cyclohexylidenemalononitrile
  • Packaging:5g
  • Price:$ 331
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  • Manufacture/Brand:Ambeed
  • Product Description:2-Cyclohexylidenemalononitrile 97%
  • Packaging:5g
  • Price:$ 201
  • Delivery:In stock
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  • Manufacture/Brand:Ambeed
  • Product Description:2-Cyclohexylidenemalononitrile 97%
  • Packaging:1g
  • Price:$ 67
  • Delivery:In stock
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  • Manufacture/Brand:Ambeed
  • Product Description:2-Cyclohexylidenemalononitrile 97%
  • Packaging:100mg
  • Price:$ 17
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  • Manufacture/Brand:Ambeed
  • Product Description:2-Cyclohexylidenemalononitrile 97%
  • Packaging:250mg
  • Price:$ 27
  • Delivery:In stock
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  • Manufacture/Brand:American Custom Chemicals Corporation
  • Product Description:2-CYCLOHEXYLIDENMALONONITRILE 95.00%
  • Packaging:1MG
  • Price:$ 586.97
  • Delivery:In stock
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Relevant articles and documentsAll total 92 Articles be found

Synthesis method of methylene malononitrile compounds

-

Paragraph 0029-0033; 0059-0062, (2020/04/02)

The invention discloses a synthesis method of methylene malononitrile compounds. According to the method, in the air atmosphere, a ketone compound and malononitrile are taken as raw materials, Ru/C istaken as a catalyst, the raw materials and the catalyst

Site-specific role of bifunctional graphitic carbon nitride catalyst for the sustainable synthesis of 3,3-spirocyclic oxindoles in aqueous media

Dandia, Anshu,Gupta, Shyam L.,Mahawar, Dinesh Kumar,Parewa, Vijay,Rathore, Kuldeep S.,Saini, Pratibha,Saini, Surendra

, p. 28452 - 28465 (2021/09/22)

Functionalized graphitic carbon nitride (Sg-C3N4) has been manufactured and used as a reusable catalyst for the one-pot production of various spiro-pyrano chromenes and spiro indole-3,1′-naphthalene tetracyclic systems in aqueous med

Knoevenagel condensation reaction on a new highly-efficient La2O2CO3-TiO2 mixed oxide catalyst: Composition-effects on C[dbnd]C bond formation

Wang, Fei,Hu, Kai,Bi, Yanshuai,Wei, Xuejiao,Xue, Bing

, (2020/08/10)

The highly efficient catalytic abilities of some mixed oxides are due to cooperative interactions between acid and base functional groups present in their active sites. New La2O2CO3-TiO2 mixed oxide catalysts wi

Asymmetric organocatalytic vinylogous Michael addition triggered triple-cascade reactions of 2-hydroxycinnamaldehydes and vinylogous nucleophiles: construction of benzofused oxabicyclo[3.3.1]nonane scaffolds

Wu, Hui-Chun,Wang, Chen,Chen, Ying-Han,Liu, Yan-Kai

supporting information, p. 1762 - 1765 (2021/02/27)

An organocatalytic vinylogous Michael addition triggered triple-cascade reaction has been developed. 2-Hydroxycinnamaldehydes worked under iminium activation with either acyclic or cyclic ketone-derived α,α-dicyanoalkenes, yielding the benzofused oxabicyclo[3.3.1]nonanes bearing one quaternary stereocenter with excellent stereoselectivities.

An Ionic Liquid on a Porous Organic Framework Support: A Recyclable Catalyst for the Knoevenagel Condensation in an Aqueous System

Chen, Peng,Sun, Jin-Shi,Wu, Xian-Tao,Xiao, En-Kai,Zhang, Lei,Zhu, Guangshan

, p. 943 - 947 (2020/06/01)

Porous aromatic frameworks (PAFs) that feature a high density of phenyl rings in their robust frameworks are attractive platforms for catalysis because of their extremely high stability, high surface area, and adjustable pore size. In this paper, two PAF-

Process route upstream and downstream products

Process route

1,3-dioxolane-2-spirocyclohexane
177-10-6

1,3-dioxolane-2-spirocyclohexane

malononitrile
109-77-3

malononitrile

2-(cyclohexylidene)malononitrile
4354-73-8

2-(cyclohexylidene)malononitrile

Conditions
ConditionsYield
68%
diethyl malonate
105-53-3

diethyl malonate

2-(cyclohexylidene)malononitrile
4354-73-8

2-(cyclohexylidene)malononitrile

Conditions
ConditionsYield
With1-butyl-3-methylimidazolium hydroxide; at 25 - 30 ℃; for 0.5h;
87%
cyclohexanol
108-93-0

cyclohexanol

2-(cyclohexylidene)malononitrile
4354-73-8

2-(cyclohexylidene)malononitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dihydrogen peroxide / water / 10 h / 90 °C / Green chemistry
2: tungstate-loaded triazine-based magnetic poly(bis-imidazolium ionic liquid) / water / 5 h / 20 °C / Green chemistry
Withdihydrogen peroxide;Inwater;2: |Knoevenagel Condensation;
malononitrile
109-77-3

malononitrile

2-(cyclohexylidene)malononitrile
4354-73-8

2-(cyclohexylidene)malononitrile

Conditions
ConditionsYield
hydrotalcite structure integrating fluoride ions;InDMF (N,N-dimethyl-formamide);at 25 ℃; for 2h; Conversion of starting material;
100%
100%
99%
WithSn-MCM-41;Intoluene;at 100 ℃; for 2h;
99%
99%
Withpolystyrene-supported DABCO;Inmethanol;at 25 ℃; for 0.25h; Green chemistry;
99%
Withpyridine; molybdenum hexacarbonyl; at 140 ℃; for 5h; Inert atmosphere;
98%
With1,4-diaza-bicyclo[2.2.2]octane;Inwater;at 20 ℃; for 0.05h; Green chemistry;
98%
WithZn(2+)*C14H8O5(2-)*C22H16N4;Inmethanol;at 60 ℃; for 24h;
98%
With5% active carbon-supported ruthenium;Inethanol;at 78 ℃; for 12h; Temperature;
98%
WithNa8H[PW9O34]*7H2O;Inmethanol;at 25 ℃; for 6h;
97%
WithZn(1+)*C5H8NO2(1-);Inwater;at 80 ℃; for 0.166667h;
96%
95%
Withammonium acetate; acetic acid;Inbenzene;at 130 ℃; Dean-Stark;
95%
Withammonium acetate; acetic acid;Inbenzene;at 130 ℃; Dean-Stark;
95%
95%
95%
94%
93%
hydrotalcite;Invarious solvent(s);at 50 ℃; for 9h;
91%
Withmorpholine; methanesulfonic acid; at 120 ℃; for 0.25h; Neat (no solvent);
91%
Withmultifunctional conjugated microporous polymer (MFCMP-1);In1,4-dioxane; water;at 25 ℃; for 4h; Catalytic behavior;
91%
Withammonium acetate; acetic acid;Intoluene;for 24h; Reflux;
90%
WithC9H20NO2(1+)*C2H3O2(1-);Inwater;at 25 ℃; for 20h; Green chemistry;
90%
With1,4-diaza-bicyclo[2.2.2]octane;Inwater;at 20 ℃; for 0.116667h; Green chemistry;
89%
modified Amberlite IRC-50 resin;Inbenzene;for 0.0833333h; Ambient temperature;
86%
85%
Withammonium acetate; acetic acid;Intoluene;Dean-Stark; Reflux;
84%
82%
82%
Withammonium acetate; acetic acid;Inbenzene;at 130 ℃; Dean-Stark;
80%
79%
79%
77%
Withpotassium carbonate; at 20 ℃; for 0.166667h;
75%
72%
Withmontmorillonite K-10; for 0.133333h; microwave irradiation;
68%
Withammonium acetate; acetic acid;Inbenzene;for 6h; Heating;
67%
67%
malononitrile;Inneat (no solvent);at 25 - 30 ℃; for 0.5h;
67%
Withsilica gel;Inneat (no solvent);for 0.05h; Irradiation;
64%
Inwater;at 65 ℃; for 4h;
62%
Withtriethylamine;Inethanol;for 0.5h; Reflux;
60%
Withpotassium fluoride on basic alumina;In1,2-dimethoxyethane;for 15h; Ambient temperature;
55%
aluminium phosphate aluminium oxide catalyst;for 0.5h; Ambient temperature;
52%
52%
42%
Withsodium acetate;Inethanol;at 20 ℃; Inert atmosphere;
30%
Withammonium acetate; acetic acid;Inbenzene;for 24h; Heating;
hydrotalcite;Intoluene;for 0.5h; Ambient temperature;
100 % Spectr.
99 % Chromat.
at 0 ℃; for 0.75h;
WithL-proline;Inwater;at 25 ℃; for 48h;
Withammonium acetate; acetic acid;Inbenzene;for 6h; Heating;
Inwater;at 25 ℃; for 48h;
75 %Spectr.
Withcetylpyridinium chloride;Intetrahydrofuran;at 80 ℃; for 12h;
Withtris(2-hydroxyethyl)ammonium acetate; at 20 ℃; for 4h;
Withammonium acetate; acetic acid;Inbenzene;Inert atmosphere; Reflux;
With[BmIm]OH;Inethanol;Reflux;
Withammonium acetate; acetic acid;Intoluene;for 2h; Reflux; Dean-Stark trap;
Withpara-xylene;Intoluene;at 80 ℃; for 1.5h;
91 %Chromat.
89.8 %Chromat.
Withammonium acetate; acetic acid;Intoluene;for 24h; Reflux;
Withammonium acetate; acetic acid;Intoluene;Dean-Stark; Reflux;
Withtriethylamine; for 18h; Reflux;
With0.04O40PW12(3-)*0.73Mg(2+)*0.22Al(3+)*2HO(1-)*0.98H2O;Inwater; isopropyl alcohol;at 60 ℃; for 6h; chemoselective reaction;
96 %Chromat.
Withammonium acetate; acetic acid;Intoluene;Reflux; Dean-Stark;
WithNb6O19(8-)*7K(1+)*H(1+)*13H2O;Inethanol;at 25 ℃; for 3h;
99 %Chromat.
With[Zn2(4,4'-(hexafluoroisopropylidene)bis(benzoic acid))2(2,5-bis(4-pyridyl)-3,4-diaza-2,4-hexadiene)];Inwater;at 20 ℃; for 0.0833333h; Reagent/catalyst; Catalytic behavior; Green chemistry;
Withtriethylamine;Inethanol;at 20 ℃; for 2h;
Withammonium acetate; acetic acid;Intoluene;Reflux; Dean-Stark;
Withmolybdenum carbide;Inwater;at 20 ℃; for 5h; Inert atmosphere; Green chemistry;
98 %Chromat.
Withmorpholine;Inethanol;at 20 ℃; Reagent/catalyst; Solvent; Catalytic behavior;
89.7 %Chromat.
Withaluminum oxide;Inchloroform;at 20 ℃;
2-(cyclohexylidene)malononitrile
4354-73-8

2-(cyclohexylidene)malononitrile

Conditions
ConditionsYield
dibromomalononitrile
1885-23-0

dibromomalononitrile

cyclohexene
110-83-8

cyclohexene

2-(cyclohexylidene)malononitrile
4354-73-8

2-(cyclohexylidene)malononitrile

Conditions
ConditionsYield
2-(4-methoxyphenylmethylene)malononitrile
2826-26-8

2-(4-methoxyphenylmethylene)malononitrile

2-(cyclohexylidene)malononitrile
4354-73-8

2-(cyclohexylidene)malononitrile

Conditions
ConditionsYield
Withtriethylamine;Inethanol;Heating;
Benzylidenemalononitrile
2700-22-3

Benzylidenemalononitrile

2-(cyclohexylidene)malononitrile
4354-73-8

2-(cyclohexylidene)malononitrile

Conditions
ConditionsYield
Withtriethylamine;Inethanol;Heating;
cyclohexanethione
2720-41-4

cyclohexanethione

malononitrile
109-77-3

malononitrile

2-(cyclohexylidene)malononitrile
4354-73-8

2-(cyclohexylidene)malononitrile

Conditions
ConditionsYield
dibromomalononitrile
1885-23-0

dibromomalononitrile

2-(cyclohexylidene)malononitrile
4354-73-8

2-(cyclohexylidene)malononitrile

Conditions
ConditionsYield
Withcopper;

Global suppliers and manufacturers

Global( 4) Suppliers
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  • Antimex Chemical Limied
  • Business Type:Lab/Research institutions
  • Contact Tel:0086-21-50563169
  • Emails:anthony@antimex.com
  • Main Products:151
  • Country:China (Mainland)
  • Finetech Industry Limited
  • Business Type:Trading Company
  • Contact Tel:86-27-87465837
  • Emails:sales@finetechnology-ind.com
  • Main Products:29
  • Country:China (Mainland)
  • Debye Scientific
  • Business Type:Lab/Research institutions
  • Contact Tel:+85221376140
  • Emails:sales@debyesci.com
  • Main Products:13
  • Country:China (Mainland)
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